1497-1566 AD., Spain, Castilia and Leon, Carlos I til Felipe II, in the name of Fernando V and Isabella, Sevilla mint, 1 Real, Cal. 379.

Spain, Castilia and Leon, Carlos I til Felipe II (ca. 1497-1566), in the name of Fernando V. and Isabella (Reyes Catolicos), Sevilla mint, struck 1497-1566 AD.,
1 Real (ø 21-23 mm / 2,47 g), 0.931 silver, ca. 3,40 g. mint weight and 28 mm die diameter, axis irregular alignment ↑→ (ca. 90°), irregular round shape with cropped edges,
Obv.: [FERNANDVS : ET : ELIS]ABET : D / S - * , legend around shield with arms of Castilia and Leon, Aragon, Sicilia and Granada in beaded circle, S and eight pointed star flanking - alrededor de un círculo de puntos que contiene el escudo coronado con las armas de Castilla-León y Aragón-Sicilia, y Granada en punta.
Rev.: [REX · ET · REGINA · CASTELE · LEGIO ARAGO - or - REX·ET·REGINA·CAST·LEGION] (or similar) , legend around yoke above bunch of arrows in beaded circle - alrededor de un círculo de puntos que contiene el Yugo y flechas, dentro en el campo, marcas de ceca y ensayador.
Cayon (1998) 2583 ; Cal. 379 .

Some examples of the many variants and from different mints:

Year / Mint Mark / Mintage
ND (1497-1566) +T Cal#411
ND (1497-1566) A Cal#302
ND (1497-1566) B : and cross at end of legend in rev.,Cal#285
ND (1497-1566) C Cuenca
ND (1497-1566) DS Cal#377
ND (1497-1566) G crosses on circles,Cal#321
ND (1497-1566) G crosses,Cal#318
ND (1497-1566) MT Cal#412
ND (1497-1566) oo Cal#300
ND (1497-1566) P aqueduct in rev.,Cal#341
ND (1497-1566) RG Cal#331
ND (1497-1566) S ** in obv.,mintmark in rev.,Cal#367
ND (1497-1566) S mintmark in rev.,Cal#358
ND (1497-1566) S* mintmark in rev.,Cal#359
ND (1497-1566) SS Cal#386
ND (1497-1566) TM Cal#406

Burgos Cal#283-298
Coruna Cal#299-303
Cuenca Cal#304-315
Granada Cal#316-335
Segovia Cal#336-354
Seville Cal#355-387
Toledo Cal#403-415